Symptoms:
When you open Google Chrome, you receive a pop-up error message that says “Your profile could not be opened correctly. Some features may be unavailable. Please check that the profile exists and you have permission to read and write its contents.
Solutions:
Mac OSX
Quit Google Chrome.
Open Terminal.
Change directory (cd) to /Users/{user}/Library/Application Support/Google/Chrome/Default
Delete Web Data and History files: rm -rf History*; rm -rf Web\ Data;
Start Google Chrome and the error should be gone.
Windows 7
Quit Google Chrome.
Open Computer.
Navigate to C:\Users\{username}\AppData\Local\Google\Chrome\User Data\Default\
Delete the file named “Web Data”
Start Google Chrome and the error should be gone.
Windows XP
Quit Google Chrome.
Open Computer.
Turn on Show Hidden Files and Foldesr in Folder Options in Windows Explorer.
Navigate to: C:\Documents and Settings\{username}\Local Settings\Application Data\Google\Chrome\User Data\
Delete the file named “Web Data”
Start Google Chrome and the error should be gone.
Linux
Quit Google Chrome.
Open a shell.
Change directory (cd) to ~/.config/google-chrome/Default
Delete the file named “Web Data”: rm -rf Web\ Data;
Start Google Chrome and the error should be gone.
NOTE: If the problem repeats itself after every reboot, then there is most likely corruption is your user profile, so you will have to delete the profile and start a new one. In order to do that, follow the above steps, and replace step 5 and 6 with the following. Make sure that you backup your bookmarks before doing this, as they are a part of your profile and will disappear after doing this:
Locate the folder called “Default” in the directory window that opens and rename it as “Backup default.”
Try opening Google Chrome again. A new “Default” folder is automatically created as you start using the browser.
More info can be found at.
http://www.fourleaftechnology.com/index.php/General/google-chrome-profile-could-not-be-opened-correctly-error.html